For active adults, though, the same mechanisms can create a different challenge
Half-life: 2.4 hours
Changes in thyroid function have been observed in some studies of rapid weight loss, though there is no established causal link between GLP-1 receptor agonists and clinically significant thyroid dysfunction in humans
Eligible studies consisted of randomized controlled trials (RCTs) involving adults with T2DM that lasted at least eight weeks and compared twice-daily Exenatide (EBID), once-weekly Exenatide (EQW), Semaglutide, Albiglutide, Lixisenatide, Dulaglutide, Liraglutide, or Tirzepatide against one another, placebo, or conventional antidiabetic therapies such as insulin, metformin, sodium-dependent glucose transporter 2 inhibitors, dipeptidyl peptidase-4 inhibitors, or sulfonylureas